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Optimized 3D Culture of Hepatic Cells for Liver Organoid Metabolic Assays

The liver is among the principal organs for glucose homeostasis and metabolism. Studies of liver metabolism are limited by the inability to expand primary hepatocytes in vitro while maintaining their metabolic functions. Human hepatic three-dimensional (3D) organoids have been established using defi...

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Detalles Bibliográficos
Autores principales: Gamboa, Christian Moya, Wang, Yujue, Xu, Huiting, Kalemba, Katarzyna, Wondisford, Fredric E., Sabaawy, Hatem E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699701/
https://www.ncbi.nlm.nih.gov/pubmed/34943788
http://dx.doi.org/10.3390/cells10123280