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CoRE-ATAC: A deep learning model for the functional classification of regulatory elements from single cell and bulk ATAC-seq data

Cis-Regulatory elements (cis-REs) include promoters, enhancers, and insulators that regulate gene expression programs via binding of transcription factors. ATAC-seq technology effectively identifies active cis-REs in a given cell type (including from single cells) by mapping accessible chromatin at...

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Detalles Bibliográficos
Autores principales: Thibodeau, Asa, Khetan, Shubham, Eroglu, Alper, Tewhey, Ryan, Stitzel, Michael L., Ucar, Duygu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699717/
https://www.ncbi.nlm.nih.gov/pubmed/34898596
http://dx.doi.org/10.1371/journal.pcbi.1009670