Phenobarbital Induces SLC13A5 Expression through Activation of PXR but Not CAR in Human Primary Hepatocytes

Phenobarbital (PB), a widely used antiepileptic drug, is known to upregulate the expression of numerous drug-metabolizing enzymes and transporters in the liver primarily via activation of the constitutive androstane receptor (CAR, NR1I3). The solute carrier family 13 member 5 (SLC13A5), a sodium-cou...

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Detalles Bibliográficos
Autores principales: Li, Zhihui, Li, Linhao, Heyward, Scott, Men, Shuaiqian, Xu, Meishu, Sueyoshi, Tatsuya, Wang, Hongbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699749/
https://www.ncbi.nlm.nih.gov/pubmed/34943889
http://dx.doi.org/10.3390/cells10123381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699749/
https://www.ncbi.nlm.nih.gov/pubmed/34943889
http://dx.doi.org/10.3390/cells10123381

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