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TGFβ Drives Metabolic Perturbations during Epithelial Mesenchymal Transition in Pancreatic Cancer: TGFβ Induced EMT in PDAC

SIMPLE SUMMARY: Pancreatic cancer is an aggressive disease with most patients diagnosed at late stages resulting in poor outcomes. While it is known that pancreatic tumor cells undergo epithelial to mesenchymal transition, the metabolic alterations accompanying that transition are not characterized....

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Detalles Bibliográficos
Autores principales: Rajagopal, Meena U., Bansal, Shivani, Kaur, Prabhjit, Jain, Shreyans K., Altadil, Tatiana, Hinzman, Charles P., Li, Yaoxiang, Moulton, Joanna, Singh, Baldev, Bansal, Sunil, Chauthe, Siddheshwar Kisan, Singh, Rajbir, Banerjee, Partha P., Mapstone, Mark, Fiandaca, Massimo S., Federoff, Howard J., Unger, Keith, Smith, Jill P., Cheema, Amrita K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699757/
https://www.ncbi.nlm.nih.gov/pubmed/34944824
http://dx.doi.org/10.3390/cancers13246204