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Unlike Brief Inhibition of Microglia Proliferation after Spinal Cord Injury, Long-Term Treatment Does Not Improve Motor Recovery

Microglia are major players in scar formation after an injury to the spinal cord. Microglia proliferation, differentiation, and survival are regulated by the colony-stimulating factor 1 (CSF1). Complete microglia elimination using CSF1 receptor (CSF1R) inhibitors worsens motor function recovery afte...

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Detalles Bibliográficos
Autores principales: Poulen, Gaëtan, Bartolami, Sylvain, Noristani, Harun N., Perrin, Florence E., Gerber, Yannick N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699766/
https://www.ncbi.nlm.nih.gov/pubmed/34942945
http://dx.doi.org/10.3390/brainsci11121643