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In Silico Approaches to Identify Polyphenol Compounds as α-Glucosidase and α-Amylase Inhibitors against Type-II Diabetes

Type-II diabetes mellitus (T2DM) results from a combination of genetic and lifestyle factors, and the prevalence of T2DM is increasing worldwide. Clinically, both α-glucosidase and α-amylase enzymes inhibitors can suppress peaks of postprandial glucose with surplus adverse effects, leading to effort...

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Detalles Bibliográficos
Autores principales: Riyaphan, Jirawat, Pham, Dinh-Chuong, Leong, Max K., Weng, Ching-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699780/
https://www.ncbi.nlm.nih.gov/pubmed/34944521
http://dx.doi.org/10.3390/biom11121877