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GPER Agonist G-1 Disrupts Tubulin Dynamics and Potentiates Temozolomide to Impair Glioblastoma Cell Proliferation

Glioblastoma (GBM) is the most common brain tumor in adults, which is very aggressive, with a very poor prognosis that affects men twice as much as women, suggesting that female hormones (estrogen) play a protective role. With an in silico approach, we highlighted that the expression of the membrane...

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Detalles Bibliográficos
Autores principales: Hirtz, Alex, Lebourdais, Nolwenn, Rech, Fabien, Bailly, Yann, Vaginay, Athénaïs, Smaïl-Tabbone, Malika, Dubois-Pot-Schneider, Hélène, Dumond, Hélène
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699794/
https://www.ncbi.nlm.nih.gov/pubmed/34943948
http://dx.doi.org/10.3390/cells10123438