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Patient-Derived Xenografts of High-Grade Serous Ovarian Cancer Subtype as a Powerful Tool in Pre-Clinical Research

SIMPLE SUMMARY: Patient-derived xenografts (PDXs) have gained popularity as a model system in anti-cancer drug development. PDXs are established by the transfer of patient tumors directly into mice without prior in vitro manipulation, assuming that these models closely resemble patient tumors. Howev...

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Detalles Bibliográficos
Autores principales: Cybula, Magdalena, Wang, Lin, Wang, Luyao, Drumond-Bock, Ana Luiza, Moxley, Katherine M., Benbrook, Doris M., Gunderson-Jackson, Camille, Ruiz-Echevarria, Maria J., Bhattacharya, Resham, Mukherjee, Priyabrata, Bieniasz, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699796/
https://www.ncbi.nlm.nih.gov/pubmed/34944908
http://dx.doi.org/10.3390/cancers13246288