Cargando…

Patient-Derived Xenografts of High-Grade Serous Ovarian Cancer Subtype as a Powerful Tool in Pre-Clinical Research

SIMPLE SUMMARY: Patient-derived xenografts (PDXs) have gained popularity as a model system in anti-cancer drug development. PDXs are established by the transfer of patient tumors directly into mice without prior in vitro manipulation, assuming that these models closely resemble patient tumors. Howev...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cybula, Magdalena, Wang, Lin, Wang, Luyao, Drumond-Bock, Ana Luiza, Moxley, Katherine M., Benbrook, Doris M., Gunderson-Jackson, Camille, Ruiz-Echevarria, Maria J., Bhattacharya, Resham, Mukherjee, Priyabrata, Bieniasz, Magdalena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699796/ https://www.ncbi.nlm.nih.gov/pubmed/34944908 http://dx.doi.org/10.3390/cancers13246288

Ejemplares similares

Increased expression of BRD4 isoforms long (BRD4-L) and short (BRD4-S) promotes chemotherapy resistance in high-grade serous ovarian carcinoma
por: Drumond-Bock, Ana Luiza, et al.
Publicado: (2023)

Multi-kinase targeted therapy as a promising treatment strategy for ovarian tumors expressing sfRon receptor
por: Wang, Luyao, et al.
Publicado: (2020)

The role of distinct BRD4 isoforms and their contribution to high-grade serous ovarian carcinoma pathogenesis
por: Drumond-Bock, Ana Luiza, et al.
Publicado: (2021)

Cloning BRD4 long isoform into overexpression vectors for stable overexpression of BRD4-L in mammalian cells
por: Drumond-Bock, Ana Luiza, et al.
Publicado: (2022)

Patient-derived tumor models are attractive tools to repurpose drugs for ovarian cancer treatment: pre-clinical updates
por: Cybula, Magdalena, et al.
Publicado: (2022)

Upregulation of Succinate Dehydrogenase (SDHA) Contributes to Enhanced Bioenergetics of Ovarian Cancer Cells and Higher Sensitivity to Anti-Metabolic Agent Shikonin
por: Wang, Lin, et al.
Publicado: (2022)

Short-form Ron is a novel determinant of ovarian cancer initiation and progression
por: Moxley, Katherine M., et al.
Publicado: (2016)

Switching the intracellular pathway and enhancing the therapeutic efficacy of small interfering RNA by auroliposome
por: Hossen, Md. Nazir, et al.
Publicado: (2020)

Targeting BMI1 mitigates chemoresistance in ovarian cancer
por: Dey, Anindya, et al.
Publicado: (2022)

BMI1, a new target of CK2α
por: Banerjee Mustafi, Soumyajit, et al.
Publicado: (2017)

When the chains do not break: the role of USP10 in physiology and pathology
por: Bhattacharya, Udayan, et al.
Publicado: (2020)

Src homology 2 (SH2) domain containing protein tyrosine phosphatase-1 (SHP-1) dephosphorylates VEGF Receptor-2 and attenuates endothelial DNA synthesis, but not migration*
por: Bhattacharya, Resham, et al.
Publicado: (2008)

Histologic and molecular analysis of patient derived xenografts of high-grade serous ovarian carcinoma
por: Dong, Ruifen, et al.
Publicado: (2016)

Subtyping of high grade serous ovarian carcinoma: histopathological and immunohistochemical approach
por: Khashaba, Marwa, et al.
Publicado: (2022)

Gold Nanoparticles sensitize pancreatic cancer cells to gemcitabine
por: Huai, Yanyan, et al.
Publicado: (2019)

High-grade serous ovarian cancer: the clone wars
por: Salomon-Perzyński, Aleksander, et al.
Publicado: (2017)

Intracellular gold nanoparticles enhance non-invasive radiofrequency thermal destruction of human gastrointestinal cancer cells
por: Gannon, Christopher J, et al.
Publicado: (2008)

Inorganic phosphate nanorods are a novel fluorescent label in cell biology
por: Patra, Chitta Ranjan, et al.
Publicado: (2006)

Classification of Molecular Subtypes of High-Grade Serous Ovarian Cancer by MALDI-Imaging
por: Kassuhn, Wanja, et al.
Publicado: (2021)

Sera Protein Signatures of Endometrial Cancer Lymph Node Metastases
por: Benbrook, Doris Mangiaracina, et al.
Publicado: (2022)

Molecular Abnormalities in Ovarian Cancer Subtypes Other than High-Grade Serous Carcinoma
por: Gilks, C. Blake
Publicado: (2010)

Histopathological subtyping of high-grade serous ovarian cancer using whole slide imaging
por: Miyagawa, Chiho, et al.
Publicado: (2023)

Small Non-Coding-RNA in Gynecological Malignancies
por: Dwivedi, Shailendra Kumar Dhar, et al.
Publicado: (2021)

Evaluation of I-TAC as a potential early plasma marker to differentiate between critical and non-critical COVID-19
por: Zhang, Yushan, et al.
Publicado: (2021)

Development of a Bioluminescent BRCA1-Deficient Xenograft Model of Disseminated, High-Grade Serous Ovarian Cancer
por: Shen, Yen Ting, et al.
Publicado: (2019)

CD24-targeted fluorescence imaging in patient-derived xenograft models of high-grade serous ovarian carcinoma
por: Kleinmanns, Katrin, et al.
Publicado: (2020)

Experimental conditions influence the formation and composition of the corona around gold nanoparticles
por: Hossen, Md. Nazir, et al.
Publicado: (2021)

Gold Nanoparticles Disrupt the IGFBP2/mTOR/PTEN Axis to Inhibit Ovarian Cancer Growth
por: Hossen, Md. Nazir, et al.
Publicado: (2022)

Molecular Characterization of an Intact p53 Pathway Subtype in High-Grade Serous Ovarian Cancer
por: Hayano, Takahide, et al.
Publicado: (2014)

Orthogonal Proteomic Platforms and Their Implications for the Stable Classification of High-Grade Serous Ovarian Cancer Subtypes
por: Thomas, Stefani N., et al.
Publicado: (2020)

Platform-Independent Classification System to Predict Molecular Subtypes of High-Grade Serous Ovarian Carcinoma
por: Shilpi, Arunima, et al.
Publicado: (2019)

The Claudin-Low Subtype of High-Grade Serous Ovarian Carcinoma Exhibits Stem Cell Features
por: Romani, Chiara, et al.
Publicado: (2021)

Distinct histopathological features are associated with molecular subtypes and outcome in low grade serous ovarian carcinoma
por: Hollis, Robert L., et al.
Publicado: (2023)

Identification of ovarian high-grade serous carcinoma cell lines that show estrogen-sensitive growth as xenografts in immunocompromised mice
por: De Haven Brandon, Alexis, et al.
Publicado: (2020)

Sensitization of ovarian cancer cells to cisplatin by gold nanoparticles
por: Xiong, Xunhao, et al.
Publicado: (2014)

Concurrent Primary Peritoneal Low-Grade Serous Carcinoma and Endometrial High-Grade Serous Carcinoma
por: Lockyer, Megan G., et al.
Publicado: (2015)

Glycoproteomics-based signatures for tumor subtyping and clinical outcome prediction of high-grade serous ovarian cancer
por: Pan, Jianbo, et al.
Publicado: (2020)

Differential expression of estrogen receptor subtypes in ovarian high‐grade serous carcinoma and clear cell carcinoma
por: Osaku, Daiken, et al.
Publicado: (2021)

Cystathionine β-Synthase Is Necessary for Axis Development in Vivo
por: Prabhudesai, Shubhangi, et al.
Publicado: (2018)

Corrigendum: Cystathionine β-Synthase Is Necessary for Axis Development in vivo
por: Prabhudesai, Shubhangi, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_nnq8gf1sl23eoon806thh2f2pf