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Harnessing Macrophages through the Blockage of CD47: Implications for Acute Myeloid Leukemia

SIMPLE SUMMARY: The immune system is the first line of protection against infected and tumor cells. Macrophages are specialized immune cells that recognize these abnormal cells and eliminate them by a mechanism called phagocytosis. All normal cells express a protein called CD47 or “don’t eat me sign...

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Detalles Bibliográficos
Autores principales: Melo Garcia, Luciana, Barabé, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699809/
https://www.ncbi.nlm.nih.gov/pubmed/34944878
http://dx.doi.org/10.3390/cancers13246258