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Geniposide Ameliorated Dexamethasone-Induced Cholesterol Accumulation in Osteoblasts by Mediating the GLP-1R/ABCA1 Axis

Background: Overexposure to glucocorticoid (GC) produces various clinical complications, including osteoporosis (OP), dyslipidemia, and hypercholesterolemia. Geniposide (GEN) is a natural iridoid compound isolated from Eucommia ulmoides. Our previous study found that GEN could alleviate dexamethason...

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Detalles Bibliográficos
Autores principales: Zheng, Yizhou, Xiao, Yaosheng, Zhang, Di, Zhang, Shanshan, Ouyang, Jing, Li, Linfu, Shi, Weimei, Zhang, Rui, Liu, Hai, Jin, Qi, Chen, Zhixi, Xu, Daohua, Wu, Longhuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699812/
https://www.ncbi.nlm.nih.gov/pubmed/34943934
http://dx.doi.org/10.3390/cells10123424