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Mouse Models of Frequently Mutated Genes in Acute Myeloid Leukemia

SIMPLE SUMMARY: Acute myeloid leukemia is a genetically heterogeneous disease and shows variable treatment outcomes. Genetic profiling has revealed different driver mutations in AML patients. Therefore, it is important to understand the biological impact of these mutations in leukemia transformation...

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Detalles Bibliográficos
Autores principales: Mohanty, Sagarajit, Heuser, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699817/
https://www.ncbi.nlm.nih.gov/pubmed/34944812
http://dx.doi.org/10.3390/cancers13246192