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Reprogramming Human Adult Fibroblasts into GABAergic Interneurons

Direct reprogramming is an appealing strategy to generate neurons from a somatic cell by forced expression of transcription factors. The generated neurons can be used for both cell replacement strategies and disease modelling. Using this technique, previous studies have shown that γ-aminobutyric aci...

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Detalles Bibliográficos
Autores principales: Bruzelius, Andreas, Kidnapillai, Srisaiyini, Drouin-Ouellet, Janelle, Stoker, Tom, Barker, Roger A., Rylander Ottosson, Daniella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699824/
https://www.ncbi.nlm.nih.gov/pubmed/34943958
http://dx.doi.org/10.3390/cells10123450