High-Throughput Functional Analysis of CFTR and Other Apically Localized Proteins in iPSC-Derived Human Intestinal Organoids

Induced Pluripotent Stem Cells (iPSCs) can be differentiated into epithelial organoids that recapitulate the relevant context for CFTR and enable testing of therapies targeting Cystic Fibrosis (CF)-causing mutant proteins. However, to date, CF-iPSC-derived organoids have only been used to study phar...

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Detalles Bibliográficos
Autores principales: Xia, Sunny, Bozóky, Zoltán, Di Paola, Michelle, Laselva, Onofrio, Ahmadi, Saumel, Jiang, Jia Xin, Pitstick, Amy L., Jiang, Chong, Rotin, Daniela, Mayhew, Christopher N., Jones, Nicola L., Bear, Christine E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699884/
https://www.ncbi.nlm.nih.gov/pubmed/34943927
http://dx.doi.org/10.3390/cells10123419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699884/
https://www.ncbi.nlm.nih.gov/pubmed/34943927
http://dx.doi.org/10.3390/cells10123419

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