Meiotic Cas9 expression mediates gene conversion in the male and female mouse germline

Highly efficient gene conversion systems have the potential to facilitate the study of complex genetic traits using laboratory mice and, if implemented as a “gene drive,” to limit loss of biodiversity and disease transmission caused by wild rodent populations. We previously showed that such a system...

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Detalles Bibliográficos
Autores principales: Weitzel, Alexander J., Grunwald, Hannah A., Weber, Ceri, Levina, Rimma, Gantz, Valentino M., Hedrick, Stephen M., Bier, Ethan, Cooper, Kimberly L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Methods and Resources
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699911/
https://www.ncbi.nlm.nih.gov/pubmed/34941868
http://dx.doi.org/10.1371/journal.pbio.3001478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699911/
https://www.ncbi.nlm.nih.gov/pubmed/34941868
http://dx.doi.org/10.1371/journal.pbio.3001478

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