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Meiotic Cas9 expression mediates gene conversion in the male and female mouse germline
Highly efficient gene conversion systems have the potential to facilitate the study of complex genetic traits using laboratory mice and, if implemented as a “gene drive,” to limit loss of biodiversity and disease transmission caused by wild rodent populations. We previously showed that such a system...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699911/ https://www.ncbi.nlm.nih.gov/pubmed/34941868 http://dx.doi.org/10.1371/journal.pbio.3001478 |