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Dynamic optimization reveals alveolar epithelial cells as key mediators of host defense in invasive aspergillosis

Aspergillus fumigatus is an important human fungal pathogen and its conidia are constantly inhaled by humans. In immunocompromised individuals, conidia can grow out as hyphae that damage lung epithelium. The resulting invasive aspergillosis is associated with devastating mortality rates. Since infec...

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Detalles Bibliográficos
Autores principales: Ewald, Jan, Rivieccio, Flora, Radosa, Lukáš, Schuster, Stefan, Brakhage, Axel A., Kaleta, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699926/
https://www.ncbi.nlm.nih.gov/pubmed/34898608
http://dx.doi.org/10.1371/journal.pcbi.1009645