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Dynamic optimization reveals alveolar epithelial cells as key mediators of host defense in invasive aspergillosis
Aspergillus fumigatus is an important human fungal pathogen and its conidia are constantly inhaled by humans. In immunocompromised individuals, conidia can grow out as hyphae that damage lung epithelium. The resulting invasive aspergillosis is associated with devastating mortality rates. Since infec...
Autores principales: | Ewald, Jan, Rivieccio, Flora, Radosa, Lukáš, Schuster, Stefan, Brakhage, Axel A., Kaleta, Christoph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699926/ https://www.ncbi.nlm.nih.gov/pubmed/34898608 http://dx.doi.org/10.1371/journal.pcbi.1009645 |
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