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Roles of mTOR in thoracic aortopathy understood by complex intracellular signaling interactions

Thoracic aortopathy–aneurysm, dissection, and rupture–is increasingly responsible for significant morbidity and mortality. Advances in medical genetics and imaging have improved diagnosis and thus enabled earlier prophylactic surgical intervention in many cases. There remains a pressing need, howeve...

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Detalles Bibliográficos
Autores principales: Estrada, Ana C., Irons, Linda, Rego, Bruno V., Li, Guangxin, Tellides, George, Humphrey, Jay D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700007/
https://www.ncbi.nlm.nih.gov/pubmed/34898595
http://dx.doi.org/10.1371/journal.pcbi.1009683