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Roles of mTOR in thoracic aortopathy understood by complex intracellular signaling interactions
Thoracic aortopathy–aneurysm, dissection, and rupture–is increasingly responsible for significant morbidity and mortality. Advances in medical genetics and imaging have improved diagnosis and thus enabled earlier prophylactic surgical intervention in many cases. There remains a pressing need, howeve...
Autores principales: | Estrada, Ana C., Irons, Linda, Rego, Bruno V., Li, Guangxin, Tellides, George, Humphrey, Jay D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700007/ https://www.ncbi.nlm.nih.gov/pubmed/34898595 http://dx.doi.org/10.1371/journal.pcbi.1009683 |
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