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The Stiffness of Cardiac Fibroblast Substrates Exerts a Regulatory Influence on Collagen Metabolism via α2β1 Integrin, FAK and Src Kinases

Information about mechanical strain in the extracellular space is conducted along collagen fibers connected with integrins and then transmitted within cells. An aim of the study is to verify the hypothesis that the stiffness of cardiac human fibroblast substrates exerts a regulatory effect on collag...

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Detalles Bibliográficos
Autores principales: Gałdyszyńska, Małgorzata, Radwańska, Paulina, Szymański, Jacek, Drobnik, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700012/
https://www.ncbi.nlm.nih.gov/pubmed/34944014
http://dx.doi.org/10.3390/cells10123506