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Epitope profiling using computational structural modelling demonstrated on coronavirus-binding antibodies
Identifying the epitope of an antibody is a key step in understanding its function and its potential as a therapeutic. Sequence-based clonal clustering can identify antibodies with similar epitope complementarity, however, antibodies from markedly different lineages but with similar structures can e...
Autores principales: | Robinson, Sarah A., Raybould, Matthew I. J., Schneider, Constantin, Wong, Wing Ki, Marks, Claire, Deane, Charlotte M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700021/ https://www.ncbi.nlm.nih.gov/pubmed/34898603 http://dx.doi.org/10.1371/journal.pcbi.1009675 |
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