The Fusion Protein rFlaA:Betv1 Modulates DC Responses by a p38-MAPK and COX2-Dependent Secretion of PGE(2) from Epithelial Cells

Developing new adjuvants/vaccines and better understanding their mode-of-action is an important task. To specifically improve birch pollen allergy treatment, we designed a fusion protein consisting of major birch pollen allergen Betv1 conjugated to the TLR5-ligand flagellin (rFlaA:Betv1). This study...

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Detalles Bibliográficos
Autores principales: Lin, Yen-Ju, Flaczyk, Adam, Wolfheimer, Sonja, Goretzki, Alexandra, Jamin, Annette, Wangorsch, Andrea, Vieths, Stefan, Scheurer, Stephan, Schülke, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700022/
https://www.ncbi.nlm.nih.gov/pubmed/34943923
http://dx.doi.org/10.3390/cells10123415

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700022/
https://www.ncbi.nlm.nih.gov/pubmed/34943923
http://dx.doi.org/10.3390/cells10123415

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