Fragment-Sized and Bidentate (Immuno)Proteasome Inhibitors Derived from Cysteine and Threonine Targeting Warheads

Constitutive- and immunoproteasomes are part of the ubiquitin–proteasome system (UPS), which is responsible for the protein homeostasis. Selective inhibition of the immunoproteasome offers opportunities for the treatment of numerous diseases, including inflammation, autoimmune diseases, and hematolo...

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Detalles Bibliográficos
Autores principales: Kollár, Levente, Gobec, Martina, Proj, Matic, Smrdel, Lara, Knez, Damijan, Imre, Tímea, Gömöry, Ágnes, Petri, László, Ábrányi-Balogh, Péter, Csányi, Dorottya, Ferenczy, György G., Gobec, Stanislav, Sosič, Izidor, Keserű, György M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700061/
https://www.ncbi.nlm.nih.gov/pubmed/34943940
http://dx.doi.org/10.3390/cells10123431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700061/
https://www.ncbi.nlm.nih.gov/pubmed/34943940
http://dx.doi.org/10.3390/cells10123431

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