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Immunomodulatory Effects Associated with Cladribine Treatment

Cladribine is a synthetic deoxyadenosine analogue with demonstrated efficacy in patients with relapsing-remitting multiple sclerosis (MS). The main mechanism of action described for cladribine is the induction of a cytotoxic effect on lymphocytes, leading to a long-term depletion of peripheral T and...

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Detalles Bibliográficos
Autores principales: Fissolo, Nicolás, Calvo-Barreiro, Laura, Eixarch, Herena, Boschert, Ursula, Espejo, Carmen, Montalban, Xavier, Comabella, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700070/
https://www.ncbi.nlm.nih.gov/pubmed/34943995
http://dx.doi.org/10.3390/cells10123488