Fully Automated Quantitative Measurement of Serum Organic Acids via LC-MS/MS for the Diagnosis of Organic Acidemias: Establishment of an Automation System and a Proof-of-Concept Validation

Gas chromatography-mass spectrometry has been widely used to analyze hundreds of organic acids in urine to provide a diagnostic basis for organic acidemia. However, it is difficult to operate in clinical laboratories on a daily basis due to sample pretreatment processing. Therefore, we aimed to deve...

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Detalles Bibliográficos
Autores principales: Ueyanagi, Yasushi, Setoyama, Daiki, Kawakami, Daisuke, Mushimoto, Yuichi, Matsumoto, Shinya, Hotta, Taeko, Kang, Dongchon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700112/
https://www.ncbi.nlm.nih.gov/pubmed/34943431
http://dx.doi.org/10.3390/diagnostics11122195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700112/
https://www.ncbi.nlm.nih.gov/pubmed/34943431
http://dx.doi.org/10.3390/diagnostics11122195

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