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Fully Automated Quantitative Measurement of Serum Organic Acids via LC-MS/MS for the Diagnosis of Organic Acidemias: Establishment of an Automation System and a Proof-of-Concept Validation
Gas chromatography-mass spectrometry has been widely used to analyze hundreds of organic acids in urine to provide a diagnostic basis for organic acidemia. However, it is difficult to operate in clinical laboratories on a daily basis due to sample pretreatment processing. Therefore, we aimed to deve...
Autores principales: | Ueyanagi, Yasushi, Setoyama, Daiki, Kawakami, Daisuke, Mushimoto, Yuichi, Matsumoto, Shinya, Hotta, Taeko, Kang, Dongchon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700112/ https://www.ncbi.nlm.nih.gov/pubmed/34943431 http://dx.doi.org/10.3390/diagnostics11122195 |
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