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Temporal Profiling of the Cortical Synaptic Mitochondrial Proteome Identifies Ageing Associated Regulators of Stability

Synapses are particularly susceptible to the effects of advancing age, and mitochondria have long been implicated as organelles contributing to this compartmental vulnerability. Despite this, the mitochondrial molecular cascades promoting age-dependent synaptic demise remain to be elucidated. Here,...

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Detalles Bibliográficos
Autores principales: Graham, Laura C., Kline, Rachel A., Lamont, Douglas J., Gillingwater, Thomas H., Mabbott, Neil A., Skehel, Paul A., Wishart, Thomas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700124/
https://www.ncbi.nlm.nih.gov/pubmed/34943911
http://dx.doi.org/10.3390/cells10123403