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The Functional and Mechanistic Roles of Immunoproteasome Subunits in Cancer

Cell-mediated immunity is driven by antigenic peptide presentation on major histocompatibility complex (MHC) molecules. Specialized proteasome complexes called immunoproteasomes process viral, bacterial, and tumor antigens for presentation on MHC class I molecules, which can induce CD8 T cells to mo...

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Detalles Bibliográficos
Autores principales: Tripathi, Satyendra Chandra, Vedpathak, Disha, Ostrin, Edwin Justin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700164/
https://www.ncbi.nlm.nih.gov/pubmed/34944095
http://dx.doi.org/10.3390/cells10123587