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The Novel Monoacylglycerol Lipase Inhibitor MJN110 Suppresses Neuroinflammation, Normalizes Synaptic Composition and Improves Behavioral Performance in the Repetitive Traumatic Brain Injury Mouse Model

Modulation of the endocannabinoid system has emerged as an effective approach for the treatment of many neurodegenerative and neuropsychological diseases. However, the underlying mechanisms are still uncertain. Using a repetitive mild traumatic brain injury (mTBI) mouse model, we found that there wa...

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Detalles Bibliográficos
Autores principales: Selvaraj, Prabhuanand, Tanaka, Mikiei, Wen, Jie, Zhang, Yumin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700188/
https://www.ncbi.nlm.nih.gov/pubmed/34943962
http://dx.doi.org/10.3390/cells10123454