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Immuno-Metabolic Modulation of Liver Oncogenesis by the Tryptophan Metabolism

Metabolic rewiring in tumor cells is a major hallmark of oncogenesis. Some of the oncometabolites drive suppressive and tolerogenic signals from the immune system, which becomes complicit to the advent and the survival of neoplasia. Tryptophan (TRP) catabolism through the kynurenine (KYN) pathway wa...

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Detalles Bibliográficos
Autores principales: Trézéguet, Véronique, Fatrouni, Hala, Merched, Aksam J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700200/
https://www.ncbi.nlm.nih.gov/pubmed/34943977
http://dx.doi.org/10.3390/cells10123469