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Immuno-Metabolic Modulation of Liver Oncogenesis by the Tryptophan Metabolism
Metabolic rewiring in tumor cells is a major hallmark of oncogenesis. Some of the oncometabolites drive suppressive and tolerogenic signals from the immune system, which becomes complicit to the advent and the survival of neoplasia. Tryptophan (TRP) catabolism through the kynurenine (KYN) pathway wa...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700200/ https://www.ncbi.nlm.nih.gov/pubmed/34943977 http://dx.doi.org/10.3390/cells10123469 |