Cargando…

TMEM176B Regulates AKT/mTOR Signaling and Tumor Growth in Triple-Negative Breast Cancer

TMEM176B is a member of the membrane spanning 4-domains (MS4) family of transmembrane proteins, and a putative ion channel that is expressed in immune cells and certain cancers. We aimed to understand the role of TMEM176B in cancer cell signaling, gene expression, cell proliferation, and migration i...

Descripción completa

Detalles Bibliográficos
Autores principales: Kang, Chifei, Rostoker, Ran, Ben-Shumel, Sarit, Rashed, Rola, Duty, James Andrew, Demircioglu, Deniz, Antoniou, Irini M., Isakov, Lika, Shen-Orr, Zila, Bravo-Cordero, Jose Javier, Kase, Nathan, Cuajungco, Math P., Moran, Thomas M., LeRoith, Derek, Gallagher, Emily Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700203/
https://www.ncbi.nlm.nih.gov/pubmed/34943938
http://dx.doi.org/10.3390/cells10123430