Potential Combination Drug Therapy to Prevent Redox Stress and Mitophagy Dysregulation in Retinal Müller Cells under High Glucose Conditions: Implications for Diabetic Retinopathy

Chronic hyperglycemia-induced thioredoxin-interacting protein (TXNIP) expression, associated oxidative/nitrosative stress (ROS/RNS), and mitochondrial dysfunction play critical roles in the etiology of diabetic retinopathy (DR). However, there is no effective drug treatment to prevent or slow down t...

Descripción completa

Detalles Bibliográficos
Autores principales: Singh, Lalit Pukhrambam, Devi, Takhellambam S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700204/
https://www.ncbi.nlm.nih.gov/pubmed/34940029
http://dx.doi.org/10.3390/diseases9040091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700204/
https://www.ncbi.nlm.nih.gov/pubmed/34940029
http://dx.doi.org/10.3390/diseases9040091

Ejemplares similares