External signals regulate continuous transcriptional states in hematopoietic stem cells

Hematopoietic stem cells (HSCs) must ensure adequate blood cell production following distinct external stressors. A comprehensive understanding of in vivo heterogeneity and specificity of HSC responses to external stimuli is currently lacking. We performed single-cell RNA sequencing (scRNA-Seq) on f...

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Detalles Bibliográficos
Autores principales: Fast, Eva M, Sporrij, Audrey, Manning, Margot, Rocha, Edroaldo Lummertz, Yang, Song, Zhou, Yi, Guo, Jimin, Baryawno, Ninib, Barkas, Nikolaos, Scadden, David, Camargo, Fernando, Zon, Leonard I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Stem Cells and Regenerative Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700284/
https://www.ncbi.nlm.nih.gov/pubmed/34939923
http://dx.doi.org/10.7554/eLife.66512

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700284/
https://www.ncbi.nlm.nih.gov/pubmed/34939923
http://dx.doi.org/10.7554/eLife.66512

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