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Activation of Downstream mTORC1 Target Ribosomal Protein S6 Kinase (S6K) Can Be Found in a Subgroup of Dutch Patients with Granulomatous Pulmonary Disease

Mechanistic target of rapamycin complex 1 (mTORC1) has been linked to different diseases. The mTORC1 signaling pathway is suggested to play a role in the granuloma formation of sarcoidosis. Recent studies demonstrated conflicting data on mTORC1 activation in patients with sarcoidosis by measuring ac...

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Detalles Bibliográficos
Autores principales: Kraaijvanger, Raisa, Seldenrijk, Kees, Beijer, Els, Damen, Jan, Wilson, Jayne Louise, Weichhart, Thomas, Grutters, Jan C., Veltkamp, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700352/
https://www.ncbi.nlm.nih.gov/pubmed/34944053
http://dx.doi.org/10.3390/cells10123545