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Potential Mechanisms Underlying Hypoxia-Induced Diabetes in a Rodent Model: Implications for COVID-19

Previous studies reported that repetitive hypoxia in rat pups reduces insulin secretion and elevates fasting blood glucose levels; these sequelae persisted for several months. This report describes how episodic hypoxic events elevate a chloride ion exporter, K(+)-Cl(−) cotransporter-2 (KCC2), in the...

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Detalles Bibliográficos
Autores principales: Pae, Eung-Kwon, Harper, Ronald M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700366/
https://www.ncbi.nlm.nih.gov/pubmed/34943374
http://dx.doi.org/10.3390/children8121178