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TGF-β Induction of miR-143/145 Is Associated to Exercise Response by Influencing Differentiation and Insulin Signaling Molecules in Human Skeletal Muscle

Physical training improves insulin sensitivity and can prevent type 2 diabetes (T2D). However, approximately 20% of individuals lack a beneficial outcome in glycemic control. TGF-β, identified as a possible upstream regulator involved in this low response, is also a potent regulator of microRNAs (mi...

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Detalles Bibliográficos
Autores principales: Dreher, Simon I., Höckele, Selina, Huypens, Peter, Irmler, Martin, Hoffmann, Christoph, Jeske, Tim, Hastreiter, Maximilian, Moller, Anja, Birkenfeld, Andreas L., Häring, Hans-Ulrich, Peter, Andreas, Beckers, Johannes, Hrabě de Angelis, Martin, Weigert, Cora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700369/
https://www.ncbi.nlm.nih.gov/pubmed/34943951
http://dx.doi.org/10.3390/cells10123443