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7-Ketocholesterol Induces Lipid Metabolic Reprogramming and Enhances Cholesterol Ester Accumulation in Cardiac Cells

7-Ketocholesterol (7KCh) is a major oxidized cholesterol product abundant in lipoprotein deposits and atherosclerotic plaques. Our previous study has shown that 7KCh accumulates in erythrocytes of heart failure patients, and further investigation centered on how 7KCh may affect metabolism in cardiom...

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Detalles Bibliográficos
Autores principales: Cheng, Mei-Ling, Tang, Hsiang-Yu, Wu, Pei-Ting, Yang, Cheng-Hung, Lo, Chi-Jen, Lin, Jui-Fen, Ho, Hung-Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700522/
https://www.ncbi.nlm.nih.gov/pubmed/34944104
http://dx.doi.org/10.3390/cells10123597