Unravelling the Impact of the Genetic Variant rs1042058 within the TPL2 Risk Gene Locus on Molecular and Clinical Disease Course Patients with Inflammatory Bowel Disease

Background: The single nucleotide polymorphism (SNP) rs1042058 within the gene locus encoding tumor progression locus 2 (TPL2) has been recently identified as a risk gene for inflammatory bowel disease (IBD). TPL2 has been shown to regulate pro-inflammatory signaling and cytokine secretion, while in...

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Detalles Bibliográficos
Autores principales: Morsy, Yasser, Brillant, Nathalie, Franc, Yannick, Scharl, Michael, Wawrzyniak, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700574/
https://www.ncbi.nlm.nih.gov/pubmed/34944097
http://dx.doi.org/10.3390/cells10123589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700574/
https://www.ncbi.nlm.nih.gov/pubmed/34944097
http://dx.doi.org/10.3390/cells10123589

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