Cargando…

Unravelling the Impact of the Genetic Variant rs1042058 within the TPL2 Risk Gene Locus on Molecular and Clinical Disease Course Patients with Inflammatory Bowel Disease

Background: The single nucleotide polymorphism (SNP) rs1042058 within the gene locus encoding tumor progression locus 2 (TPL2) has been recently identified as a risk gene for inflammatory bowel disease (IBD). TPL2 has been shown to regulate pro-inflammatory signaling and cytokine secretion, while in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Morsy, Yasser, Brillant, Nathalie, Franc, Yannick, Scharl, Michael, Wawrzyniak, Marcin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700574/ https://www.ncbi.nlm.nih.gov/pubmed/34944097 http://dx.doi.org/10.3390/cells10123589

Ejemplares similares

Tumor Progression Locus 2 (Tpl2) Kinase as a Novel Therapeutic Target for Cancer: Double-Sided Effects of Tpl2 on Cancer
por: Lee, Hye Won, et al.
Publicado: (2015)

Genotype–phenotype associations of polymorphisms within the gene locus of NOD-like receptor pyrin domain containing 3 in Swiss inflammatory bowel disease patients
por: Yoganathan, Priyatharsan, et al.
Publicado: (2021)

Tumor Progression Locus 2 (Tpl2) Deficiency Does Not Protect against Obesity-Induced Metabolic Disease
por: Lancaster, Graeme I., et al.
Publicado: (2012)

Endothelial Barrier Disruption by Lipid Emulsions Containing a High Amount of N3 Fatty Acids (Omegaven) but Not N6 Fatty Acids (Intralipid)
por: Gueguen, Emilie, et al.
Publicado: (2022)

Tumor Progression Locus 2 (TPL2) Regulates Obesity-Associated Inflammation and Insulin Resistance
por: Perfield, James W., et al.
Publicado: (2011)

Tumor progression locus 2 (TPL2) in tumor-promoting Inflammation, Tumorigenesis and Tumor Immunity
por: Njunge, Lucy Wanjiru, et al.
Publicado: (2020)

Transcriptional and Ultrastructural Analyses Suggest Novel Insights into Epithelial Barrier Impairment in Celiac Disease
por: Sowińska, Agnieszka, et al.
Publicado: (2020)

Foot-and-Mouth Disease Virus Structural Protein VP1 Destroys the Stability of the TPL2 Trimer by Degradation of TPL2 To Evade Host Antiviral Immunity
por: Zhang, Keshan, et al.
Publicado: (2021)

Tamiz de problemas del lenguaje-TPL
por: Auza Benavides, Alejandra

TPL2/COT/MAP3K8 (TPL2) Activation Promotes Androgen Depletion-Independent (ADI) Prostate Cancer Growth
por: Jeong, Joseph H., et al.
Publicado: (2011)

Glycoprotein (GP)96 Is Essential for Maintaining Intestinal Epithelial Architecture by Supporting Its Self-Renewal Capacity
por: Häfliger, Janine, et al.
Publicado: (2022)

TPL2 kinase expression is regulated by the p38γ/p38δ-dependent association of aconitase-1 with TPL2 mRNA
por: Escós, Alejandra, et al.
Publicado: (2022)

Microbial Sensing by the Intestinal Epithelium in the Pathogenesis of Inflammatory Bowel Disease
por: Scharl, Michael, et al.
Publicado: (2010)

Spermidine Ameliorates Colitis via Induction of Anti-Inflammatory Macrophages and Prevention of Intestinal Dysbiosis
por: Niechcial, Anna, et al.
Publicado: (2023)

Expression of the Tpl2/Cot oncogene in human T-cell neoplasias
por: Christoforidou, Anna V, et al.
Publicado: (2004)

TPL2 mediates IL-17R signaling in neuroinflammation
por: Xiao, Yichuan, et al.
Publicado: (2015)

SlTPL1 Silencing Induces Facultative Parthenocarpy in Tomato
por: He, Mi, et al.
Publicado: (2021)

The impact of colectomy on the course of extraintestinal manifestations in Swiss inflammatory bowel disease cohort study patients
por: Roth, René, et al.
Publicado: (2021)

Dysbiotic microbiota interactions in Crohn’s disease
por: Caparrós, Esther, et al.
Publicado: (2021)

TPL2-NPM-p53 pathway monitors nucleolar stress
por: Eliopoulos, Aristides G., et al.
Publicado: (2015)

TPL-2 restricts Ccl24-dependent immunity to Heligmosomoides polygyrus
por: Kannan, Yashaswini, et al.
Publicado: (2017)

Extraintestinal Manifestations of Inflammatory Bowel Disease
por: Vavricka, Stephan R., et al.
Publicado: (2015)

Unraveling haplotype errors in the DFNA33 locus
por: Vona, Barbara, et al.
Publicado: (2023)

Two TPL-Binding Motifs of ARF2 Are Involved in Repression of Auxin Responses
por: Choi, Hee-Seung, et al.
Publicado: (2018)

TPL‐2 kinase induces phagosome acidification to promote macrophage killing of bacteria
por: Breyer, Felix, et al.
Publicado: (2021)

Association of rs10757274 and rs2383206 Polymorphisms on 9p21 locus with Coronary Artery Disease in Turkish Population
por: Yayla, Çağrı, et al.
Publicado: (2016)

Bugs, genes, fatty acids, and serotonin: Unraveling inflammatory bowel disease?
por: Kaunitz, Jonathan, et al.
Publicado: (2015)

Unravelling specific diet and gut microbial contributions to inflammatory bowel disease
por: Pereira, Gabriel Vasconcelos, et al.
Publicado: (2023)

Unraveling the Link between Periodontitis and Inflammatory Bowel Disease: Challenges and Outlook
por: Tanwar, Himanshi, et al.
Publicado: (2023)

Stromal Cells in the Pathogenesis of Inflammatory Bowel Disease
por: Barnhoorn, M C, et al.
Publicado: (2020)

Colorectal carcinoma in the course of inflammatory bowel diseases
por: Hnatyszyn, Andrzej, et al.
Publicado: (2019)

The Effect of Antidepressants on the Course of Inflammatory Bowel Disease
por: Hall, Barry J., et al.
Publicado: (2018)

Association Study of rs1333040 and rs1004638 Polymorphisms in the 9p21 Locus with Coronary Artery Disease in Southwest of Iran
por: Golabgir Khademi, Khadijeh, et al.
Publicado: (2016)

Effect of distance to specialist care for the diagnosis and disease outcome of inflammatory bowel disease in the Swiss inflammatory bowel disease cohort study
por: Grob, Lorenz, et al.
Publicado: (2020)

The Impact of Azathioprine-Associated Lymphopenia on the Onset of Opportunistic Infections in Patients with Inflammatory Bowel Disease
por: Vögelin, Marius, et al.
Publicado: (2016)

TPL-2 negatively regulates interferon-β production in macrophages and myeloid dendritic cells
por: Kaiser, Frank, et al.
Publicado: (2009)

Altered Prostanoid Signaling Contributes to Increased Skin Tumorigenesis in Tpl2 Knockout Mice
por: DeCicco-Skinner, Kathleen L., et al.
Publicado: (2013)

Prognostic role of TPL2 in early-stage non-small cell lung cancer
por: Boldrini, Laura, et al.
Publicado: (2017)

Tpl2 is required for VEGF-A-stimulated signal transduction and endothelial cell function
por: Fearnley, Gareth W., et al.
Publicado: (2019)

Unraveling the Impact of Gut and Oral Microbiome on Gut Health in Inflammatory Bowel Diseases
por: Elzayat, Hala, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_ukoog02mh9tfdptkpjcfr9nj11