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Transcriptomic Profiles Reveal Downregulation of Low-Density Lipoprotein Particle Receptor Pathway Activity in Patients Surviving Severe COVID-19

To assess the biology of the lethal endpoint in patients with SARS-CoV-2 infection, we compared the transcriptional response to the virus in patients who survived or died during severe COVID-19. We applied gene expression profiling to generate transcriptional signatures for peripheral blood mononucl...

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Detalles Bibliográficos
Autores principales: Vlasov, Ivan, Panteleeva, Alexandra, Usenko, Tatiana, Nikolaev, Mikhael, Izumchenko, Artem, Gavrilova, Elena, Shlyk, Irina, Miroshnikova, Valentina, Shadrina, Maria, Polushin, Yurii, Pchelina, Sofya, Slonimsky, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700658/
https://www.ncbi.nlm.nih.gov/pubmed/34944005
http://dx.doi.org/10.3390/cells10123495