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Cyclophilin A Impairs Efferocytosis and Accelerates Atherosclerosis by Overexpressing CD 47 and Down-Regulating Calreticulin

Impairment of efferocytosis in apoptotic macrophages is a known determinant of the severity of atherosclerosis and the vulnerability of plaques to rupture. The precise mechanisms involved in impaired efferocytosis are unclear. Given the well-recognized role of the inflammatory cytokine cyclophilin A...

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Detalles Bibliográficos
Autores principales: Anandan, Vinitha, Thulaseedharan, Thushara, Suresh Kumar, Aishwarya, Chandran Latha, Karthika, Revikumar, Amjesh, Mullasari, Ajit, Kartha, Chandrasekharan C., Jaleel, Abdul, Ramachandran, Surya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700718/
https://www.ncbi.nlm.nih.gov/pubmed/34944106
http://dx.doi.org/10.3390/cells10123598