Effects of Genetic Polymorphisms of Cathepsin A on Metabolism of Tenofovir Alafenamide

Cathepsin A (CatA) is important as a drug-metabolizing enzyme responsible for the activation of prodrugs, such as the anti-human immunodeficiency virus drug Tenofovir Alafenamide (TAF). The present study was undertaken to clarify the presence of polymorphisms of the CatA gene in healthy Japanese sub...

Descripción completa

Detalles Bibliográficos
Autores principales: Ito, Soichiro, Hirota, Takeshi, Yanai, Miyu, Muto, Mai, Watanabe, Eri, Taya, Yuki, Ieiri, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700939/
https://www.ncbi.nlm.nih.gov/pubmed/34946974
http://dx.doi.org/10.3390/genes12122026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700939/
https://www.ncbi.nlm.nih.gov/pubmed/34946974
http://dx.doi.org/10.3390/genes12122026

Ejemplares similares