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Effects of Genetic Polymorphisms of Cathepsin A on Metabolism of Tenofovir Alafenamide

Cathepsin A (CatA) is important as a drug-metabolizing enzyme responsible for the activation of prodrugs, such as the anti-human immunodeficiency virus drug Tenofovir Alafenamide (TAF). The present study was undertaken to clarify the presence of polymorphisms of the CatA gene in healthy Japanese sub...

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Detalles Bibliográficos
Autores principales:	Ito, Soichiro, Hirota, Takeshi, Yanai, Miyu, Muto, Mai, Watanabe, Eri, Taya, Yuki, Ieiri, Ichiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700939/ https://www.ncbi.nlm.nih.gov/pubmed/34946974 http://dx.doi.org/10.3390/genes12122026

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