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The Genetic Landscape of Patent Foramen Ovale: A Systematic Review

Patent Foramen Ovale (PFO) is a common postnatal defect of cardiac atrial septation. A certain degree of familial aggregation has been reported. Animal studies suggest the involvement of the Notch pathway and other cardiac transcription factors (GATA4, TBX20, NKX2-5) in Foramen Ovale closure. This r...

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Detalles Bibliográficos
Autores principales: Paolucci, Matteo, Vincenzi, Chiara, Romoli, Michele, Amico, Giulia, Ceccherini, Isabella, Lattanzi, Simona, Bersano, Anna, Longoni, Marco, Sacco, Simona, Vernieri, Fabrizio, Pascarella, Rosario, Valzania, Franco, Zedde, Marialuisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700998/
https://www.ncbi.nlm.nih.gov/pubmed/34946902
http://dx.doi.org/10.3390/genes12121953