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RDAClone: Deciphering Tumor Heterozygosity through Single-Cell Genomics Data Analysis with Robust Deep Autoencoder

Rapid advances in single-cell genomics sequencing (SCGS) have allowed researchers to characterize tumor heterozygosity with unprecedented resolution and reveal the phylogenetic relationships between tumor cells or clones. However, high sequencing error rates of current SCGS data, i.e., false positiv...

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Detalles Bibliográficos
Autores principales: Xia, Jie, Wang, Lequn, Zhang, Guijun, Zuo, Chunman, Chen, Luonan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8701080/
https://www.ncbi.nlm.nih.gov/pubmed/34946794
http://dx.doi.org/10.3390/genes12121847