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HLA-DQA1*05 Associates with Extensive Ulcerative Colitis at Diagnosis: An Observational Study in Children

The human leukocyte antigen (HLA) allele group HLA-DQA1*05 predisposes to ulcerative colitis (UC) and is associated with the development of antibodies against infliximab in patients with inflammatory bowel disease (IBD). Therefore, we hypothesized that the presence of HLA-DQA1*05 correlates with cha...

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Detalles Bibliográficos
Autores principales: Nowak, Jan Krzysztof, Glapa-Nowak, Aleksandra, Banaszkiewicz, Aleksandra, Iwańczak, Barbara, Kwiecień, Jarosław, Szaflarska-Popławska, Anna, Grzybowska-Chlebowczyk, Urszula, Osiecki, Marcin, Kierkuś, Jarosław, Hołubiec, Magdalena, Chanaj-Kaczmarek, Justyna, Radzikowski, Andrzej, Walkowiak, Jarosław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8701736/
https://www.ncbi.nlm.nih.gov/pubmed/34946883
http://dx.doi.org/10.3390/genes12121934