Investigation of Isocitrate Dehydrogenase 1 and 2 Mutations in Acute Leukemia Patients in Saudi Arabia

Different forms of human cancer show mutations for isocitrate dehydrogenases 1 and 2 (IDH1/2). Mutation of these genes can cause aberrant methylation of the genome CpG islands (CGIs), which leads to an increase of suppressed oncogenes transcription or repression of active tumor suppressor gene trans...

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Detalles Bibliográficos
Autores principales: Alkhatabi, Heba, Bin Saddeq, Haneen Abdulfattah, Alyamani, Luay, Shinawi, Thoraia, Yasin, Elrashed B., Alserihi, Raed, Felimban, Raed, Tayeb, Hossam H., Mimani, Rawan, Alalla, Zainab, Abu-Elmagd, Muhammad, Abuzenadah, Adel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8701864/
https://www.ncbi.nlm.nih.gov/pubmed/34946913
http://dx.doi.org/10.3390/genes12121963

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8701864/
https://www.ncbi.nlm.nih.gov/pubmed/34946913
http://dx.doi.org/10.3390/genes12121963

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