BRCA1/2 NGS Somatic Testing in Clinical Practice: A Short Report

High-grade serous ovarian carcinoma (HGSOC) is the most common subtype of all ovarian carcinomas. HGSOC harboring BRCA1/2 germline or somatic mutations are sensitive to the poly (adenosine diphosphate-ribose) polymerase inhibitors (PARPi). Therefore, detecting these mutations is crucial to identifyi...

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Detalles Bibliográficos
Autores principales: Pepe, Francesco, Pisapia, Pasquale, Russo, Gianluca, Nacchio, Mariantonia, Pallante, Pierlorenzo, Vigliar, Elena, De Angelis, Carmine, Insabato, Luigi, Bellevicine, Claudio, De Placido, Sabino, Troncone, Giancarlo, Malapelle, Umberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8702012/
https://www.ncbi.nlm.nih.gov/pubmed/34946865
http://dx.doi.org/10.3390/genes12121917

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8702012/
https://www.ncbi.nlm.nih.gov/pubmed/34946865
http://dx.doi.org/10.3390/genes12121917

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